Warner Home Video (Firm)

Their mission is simple: Find a cure. Stop the virus. Save the world. When a global pandemic wipes out eighty percent of the planet's population, the crew of a lone naval destroyer must find a way to pull humanity from the brink of extinction.

"Expectant first-time father Peter Highman (Robert Downey, Jr.) looks forward to his new child's due date five days away. As Peter hurries to catch a flight home from Atlanta to be at his wife's side for the birth, his best intentions go completely awry when an encounter with aspiring actor Ethan Tremblay (Zach Galifianakis) forces Peter to hitch a ride with Ethan on a cross-country trip that will ultimately destroy several cars, many friendships...

Based on William Brinkley's popular novel, it chronicles a global catastrophe that nearly decimates the world's population. Because of its positioning, the Navy destroyer USS Nathan James avoided falling victim to the devastating tragedy. But now the crew and its captain must confront the reality of their new existence in a world where they may be among the few remaining survivors.