Diego is an 8-year-old who is an animal rescuer with an intense love of nature and the animals around him. Diego and his friends Click the Camera and Mr. Marquez go on animal rescue adventures.

A mean magician turns all the African elephants into rocks. Diego, Alicia, and Baby Jaguar join Animal Rescuer Juma to find Erin the Elephant and a hidden magic drum that can break the spell and help all the animals in Africa. Help Diego and Alicia at Rescue Ranch when they meet Panchita, a prairie dog who needs to find a nice grassy prairie for her family. Jorge, the hawk needs to migrate, but when he loses the big hawks, he needs help from Diego....

Nursery Rhyme Land needs the gang to help the Cow jump over the moon. Then they fly into a painting to help a spider climb up the water spout. Hop on Horseyboat for a medieval mission to save a Griffin. Then help a Baby Rooster wake up the farm. Return to Puppetland to save Little Red Riding Hood from the Big Bad Wolf. Then Linny and Ming-Ming travel to the Caribbean to rescue Turtle Tuck. Then, save a Baby Panda with a bellyache and help a mouse...

Spooky hilarity and mystery abound with the crime-busting gang of Shaggy, Fred, Daphne, Velma and the ever-comical Scooby-Doo.