When an unusual solar flare damages his space shuttle and causes astronaut Hank Henshaw and his crew--including his wife--to mutate, he blames Superman and as his surviving consciousness learns to fuse with technology he vows revenge.

There is a new superhero in Metropolis, Booster Gold, but he seems more interested in glory and popularity, then in actually doing good, so a suspicious Superman decides to find out just who this person is and where he comes from--and what he is planning for the future.

Mr. Mxyzptlk, a mischievous imp from the Fifth Dimension, is on the loose in Metropolis, and causing mayhem with his tricks--so it is up to Superman to find a way to reverse the magic and send Mxy back where he belongs.

In an attempt to force the Daily Planet newspaper to stop wasting paper, Poison Ivy creates a vine of kryptonite that covers the whole building, and a seriously weakened Superman must find a way to stop her before she kills Lois and his other friends.